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Pharmacological and genetic inhibition of ARG2 in CXCR2 Hi myeloid-derived suppressor cells combats sepsis-induced lymphopenia

作者:Qiuyue Long, Shixu Song, Jiwei Li, Jialing Gan, Shuoqi Yang, Boyu Li, Hongli Ye, Binghan Zheng, Fangfang Wu, Zhichen Yu, Jing Wu, Linyu Ding, Mingzheng Jiang, Xiaoyi Hu, Zhancheng Gao, Yali Zheng · 发表于:Theranostics · 年份:2025 · DOI:10.7150/thno.112339 · 被引用次数:9 · 研究领域:Inflammation biomarkers and pathways、Sepsis Diagnosis and Treatment、Amoebic Infections and Treatments

MDSC-derived ARG2 as a promising target of immune enhancement therapy in sepsis.