Chemically synthesized phosphorylated ubiquitin unlocks parkin for activation-controlled PROTAC platforms

作者：Fangdan Chen, Qing Zhan, Qian Qu, Siyi Cui, Yicheng Weng, Man Pan, Qingyun Zheng, Honggang Hu, Yuanyuan Yu · 发表于：Science China Chemistry · 年份：2025 · DOI：10.1007/s11426-025-2762-0 · 被引用次数：6 · 研究领域：Protein Degradation and Inhibitors、Ubiquitin and proteasome pathways、Peptidase Inhibition and Analysis