Supplementary Fig.S6 from Comprehensive Characterization of Somatic Mutation Timing Reveals the Evolutionary Trajectory of Lung Adenocarcinoma in Chinese Patients

作者：Na Qin, Zhoufeng Wang, Xianfeng Xu, Yuan Xie, Yingjia Chen, Wenxin Luo, Pan Tang, Xin Wang, Lingfeng Bi, Linnan Gong, Zhe Li, Congcong Chen, Kai Wang, Songwei Guo, Zihuan Zhao, Jun Xiang, Meng Zhu, Yue Jiang, Yuanlin He, Juncheng Dai, Rong Yin, Cheng Wang, Zhibin Hu, Hongxia Ma, Weimin Li, Hongbing Shen · 年份：2025 · DOI：10.1158/0008-5472.29760715 · 研究领域：Cancer Genomics and Diagnostics、Bioinformatics and Genomic Networks、Gene expression and cancer classification

<p>Negative binomial mixed-effect model to test the non-linearity of the tumor mutational burden (TMB) of early and late clonal mutations with smoking pack-years.</p>