Multichannel bioelectronic sensing using engineered Escherichia coli

作者：Xu Zhang, Marimikel Charrier, Caroline M. Ajo‐Franklin · 发表于：Nature Communications · 年份：2025 · DOI：10.1038/s41467-025-62256-1 · 被引用次数：15 · 研究领域：Microbial Fuel Cells and Bioremediation、Molecular Communication and Nanonetworks、Neuroscience and Neural Engineering

to develop a redox-potential-dependent algorithm that efficiently converts biological signals into 2-bit binary outputs. This enables our bioelectronic sensor to detect and differentiate heavy metals at EPA limits. When deployed in complex environmental water samples, our sensor effectively and accurately encodes 2-bit binary signals across various analyte conditions. Thus, our multichannel bioelectronic sensor advances the field through simultaneous detection of different chemicals by a single cell, significantly expanding information transmission and helping to safeguard human and environmental health.