Use of the PaO2/FiO2 ratio in acute pulmonary embolism: a simple and reliable parameter to predict the risk stratification

作者：Yanan Li, Xueqing Du, Ling Zhou, Jian Guan, Yidan Sun, Xianwen Sun, Yun Feng, Dong Liu, Yongjie Ding, Guochao Shi · 发表于：Journal of Thoracic Disease · 年份：2025 · DOI：10.21037/jtd-24-1821 · 被引用次数：3 · 研究领域：Venous Thromboembolism Diagnosis and Management、Inflammatory Biomarkers in Disease Prognosis、Blood Coagulation and Thrombosis Mechanisms

Background: ) ratio (P/F ratio), in evaluating the risk stratification of APE. Methods: A retrospective analysis of demographic data, complications, clinical symptoms, and laboratory data of 227 adult patients with APE treated at Ruijin Hospital, Shanghai Jiao Tong University School of Medicine Ruijin Hospital, from January 2016 to December 2021 was conducted. According to risk stratification, patients were divided into the intermediate-low risk and below group (low-risk group and intermediate-low-risk group), intermediate-high-risk and above group (intermediate-high-risk group and high-risk group), and the correlation between various indicators and risk stratification of APE was analyzed. Multivariate binary logistic regression was used to identify independent influencing factors for intermediate-high-risk and high-risk APE; receiver operating characteristic (ROC) curve analysis was used to evaluate the efficacy of P/F ratio in assessing intermediate-high-risk and high-risk APE. Results: were correlated with the risk stratification (P<0.05). Multivariate binary logistic regression analysis showed that P/F ratio was an independent risk factor for intermediate-high-risk and high-risk APE (P=0.01). The area under the curve (AUC) of P/F ratio for predicting APE in the intermediate-high-risk group and the high-risk group was 0.850, the cut-off value was 256.41, the sensitivity was 74.2%, and the specificity was 81.6%. Conclusions: The P/F ratio has certain evaluative value in ris...