Systematic review and meta-analysis of Guipi Decoction in the treatment of anemia

作者：Xueyan Lv, Dongmei Wang, Xiangni Zou · 发表于：Medicine · 年份：2025 · DOI：10.1097/md.0000000000043625 · 被引用次数：4 · 研究领域：Iron Metabolism and Disorders、Traditional Chinese Medicine Studies、Acupuncture Treatment Research Studies

BACKGROUND: Anemia is a common and widely influential public health problem worldwide. The objective was to conduct a comprehensive and in-depth systematic evaluation of the therapeutic efficacy of Guipi Decoction as an adjuvant treatment for patients with anemia and to offer new ideas for the clinical treatment of anemia. METHODS: A comprehensive and systematic literature search was meticulously executed across multiple authoritative databases, including CNKI, Wanfang, VIP, EMBase, Scopus, Web of Science, PubMed, and the Cochrane Library. The search was designed to identify all relevant randomized controlled trials that investigated the application of Guipi Decoction as an adjuvant therapy for Anemia patients. Considering that 1 researcher had written article of this kind in 2020, so the time frame of the search spanned from January 2020 to January 2025. Two independent reviewers selected eligible trials, extracted data, and assessed methodological quality using predefined criteria. Meta-analysis was performed using the standardized software RevMan 5.3. RESULTS: A total of 13 studies were included in the final analysis, involving a cumulative sample size of 954 participants. These participants were randomly allocated to the experimental group and the control group. Pretreatment physiological parameters were comparable between the 2 groups, with no statistically significant differences, indicating a balanced randomization. Posttreatment, the experimental group demonstrated si...