O-RADS US versus IOTA simple rules in the diagnosis of benign and malignant adnexal masses: a prospective study

作者：Ya Yang, Hongyan Wang, Na Su, Luying Gao, Yang Gu, Siman Cai, Qing Dai, Jianchu Li, Yuxin Jiang · 发表于：BMC Medical Imaging · 年份：2025 · DOI：10.1186/s12880-025-01845-4 · 被引用次数：5 · 研究领域：Ovarian cancer diagnosis and treatment、Ovarian function and disorders、Endometriosis Research and Treatment

BACKGROUND: Although many studies have validated the diagnostic performance of Ovarian-Adnexal Reporting and Data Systems ultrasound (O-RADS US), most have been observed by experienced sonologists, and relatively few by junior sonologists. The purpose of this study was to compare the diagnostic performance of the O-RADS US and the International Ovarian Tumor Analysis (IOTA) Simple Rules (SRs) in senior and junior sonologists to determine a more suitable assessment model for general clinical use. METHODS: We prospectively recruited 228 patients diagnosed with adnexal masses (AMs). Two senior sonologists acquired images and evaluated them following the O-RADS US and IOTA guidelines, and two junior sonologists reviewed and analyzed images and evaluated them following the same guidelines. In this research, pathological findings were used as the reference standard. Comparisons of categorical variables were made using the chi-square test, and comparisons of continuous variables were made using the two independent-samples t-test. The diagnostic performance of the models was compared by analyzing the receiver operating characteristic (ROC) curve. The kappa value (κ) was used to compare the interobserver agreement between the senior and junior sonologists and the agreement between each ultrasound method and the reference standard. RESULTS: Of 228 AMs, 176 were benign and 52 malignant. The junior adjusted O-RADS US (> O-RADS 4a represents malignancy) had the highest diagnostic validity...