Use of extracorporeal membrane oxygenation in adult trauma patients with refractory acute cardiopulmonary failure: guideline from the Chinese society of extracorporeal life support 2025

作者：Hua Wang, Zhongran Cen, Xingxing Liu, Zhan‐Guo Liu, Xiaotong Hou, Xiangdong Guan, Jianfeng Wu, Yimin Li, Yonghao Xu, Chengbin Zhou, Zhiyong Peng, Fachun Zhou, Tongwen Sun, Bingyu Qin, Jiandong Lin, Lina Zhang, Jinghui Li, You Shang, Songqiao Liu, Zhenhua Zeng, Xiaowu Wang, Qunqing Chen, Yanwu Guo, Changbiao Peng, Yang Wang, Shaoqiu Li, Chunyao Wang, Shulin Xiang, Cheng Zhou, Peihua Cao, Jie Jiang, Yihao Chen, Duoduo Yu, Wenzhan Liao, Ye Liao, Xiaoqin Cheng, Limei Chen, Yuxuan He, Jie He, Qingling Guo, Zenghui Yue, Ke Deng, Ying Tang, Bo Huang, Cuiping Liu, Sheng Peng, Jing Cai, Yaru Zhu, Kai Wang, Yangyang Wang, Qianwen Wang, H. J. Yang, Maoyou Shichen, Zhuo Li, Manli Guo, Xueshan Luo, the Chinese Society of Extracorporeal Life Support (CSECLS) · 发表于：Critical Care · 年份：2025 · DOI：10.1186/s13054-025-05504-6 · 被引用次数：6 · 研究领域：Mechanical Circulatory Support Devices、Respiratory Support and Mechanisms、Trauma Management and Diagnosis

BACKGROUND: Adult trauma patients with refractory acute cardiopulmonary failure suffer from high morbidity and mortality. In the past decade, a growing body of researches has shown survival benefits of extracorporeal membrane oxygenation (ECMO) in trauma patients who fail to respond to optimal damage control resuscitation (DCR), and there is an opportunity to formulate clinical practice guidelines to guide clinicians in implementing trauma ECMO at the bedside. METHODS: The Chinese Society of Extracorporeal Life Support (CSECLS) convened a domestic panel of interdisciplinary experts to develop this guideline, adhering to the principles of the World Health Organization (WHO) Manual for Guideline Development and the policy of conflict of interest. Clinical key questions pertaining to trauma ECMO use were informed from expert interviews and literature reviews, and formulated as PICO (Population/Intervention/Comparison/Outcome) format for literature retrieval of original studies supporting the question. Then, panelists were assigned to address specific clinical questions, synthesize evidence, formulate recommendations and determine their strength, following the Recommendations Assessment, Development and Evaluation (GRADE) framework. The guideline steering committee and stakeholders approved the final document. RESULTS: Eleven recommendations regarding trauma ECMO use in adult patients were formulated, focusing on the following topics: (1) indications; (2) patient screening; (3) t...