Parabacteroides as a promising target for disease intervention: current stage and pending issues

作者：Jing Liu, Hui Qiu, Jiamin Zhao, Nan Shao, Nan Shao, Chao Chen, Zhixu He, Xu Zhao, Juanjuan Zhao, Juanjuan Zhao, Ya Zhou, Lin Xu · 发表于：npj Biofilms and Microbiomes · 年份：2025 · DOI：10.1038/s41522-025-00772-0 · 被引用次数：31 · 研究领域：Gut microbiota and health、Probiotics and Fermented Foods、Clostridium difficile and Clostridium perfringens research

Parabacteroides, a promising candidate for the next generation of probiotics, plays a significant role in various diseases. In this review, we provide a comprehensive examination of the biological properties of Parabacteroides, summarize its effects on host health and potential associations with diseases, and discuss unresolved scientific questions regarding this genus. Our aim is to offer novel insights for the development of targeted gut microbiota interventions and their translational applications.