Attention/Working Memory and Executive Function in Parkinson's Disease: Review, Critique, and Recommendations

作者：Roberta Biundo, Ondřej Bezdíček, Davide Maria Cammisuli, Brenna Cholerton, John C. Dalrymple‐Alford, Nicola M.J. Edelstyn, Eleonora Fiorenzato, Erin Holker, Saül Martínez‐Horta, Alice Martini, Gabriella Santangelo, Bàrbara Segura, Chiara Siri, Alexander I. Tröster, Tiago Mestre, Álvaro Sánchez‐Ferro, Michelle Hyczy de Siqueira Tosin, Matěj Škorvánek, Daniel Weintraub, Gert J. Geurtsen · 发表于：Movement Disorders · 年份：2025 · DOI：10.1002/mds.30293 · 被引用次数：16 · 研究领域：Parkinson's Disease Mechanisms and Treatments、Voice and Speech Disorders、Balance, Gait, and Falls Prevention

BACKGROUND: Cognitive impairment in Parkinson's disease (PD) is a well-established non-motor complication that significantly affects the quality of life and well-being of both patients and care partners. To optimally detect mild cognitive impairment or dementia, extensive neuropsychological assessment is essential. A wide range of cognitive tests and clinical outcome assessments have been used in clinical settings, often without regard to their clinimetric quality. METHODS: We performed a literature review of tests assessing attention/working memory and executive domains in PD (tests on other domains are included in an accompanying review). The selected tests were evaluated for their clinimetric properties and categorized by a panel of experts as "recommended," "recommended with caveats," "suggested," or "listed" according to the International Parkinson and Movement Disorder Society Clinical Outcome Assessment Scientific Evaluation Committee guidelines. RESULTS: A total of 30 tests were reviewed. Eight tests were "recommended," including four tests assessing attention/working memory abilities (WAIS-IV Digit Span, Coding and Symbol Search subtests, and Trail Making Test) and four tests assessing executive abilities (WAIS-IV Similarities, Wisconsin Card Sorting Test, Fluency Tests, and Stroop Color-Word Test). These tests demonstrated good to excellent levels of reliability and validity, have normative datasets, and are sensitive to change. Eight other tests were "recommended w...