Age Differences in Cannabis Consumption Patterns and in Associations Between Delta-9-Tetrahydrocannabinol Intake and Cannabis Use Disorders Among Adults with Daily Use

作者：Ofir Livne, Jacob T. Borodovsky, Alan J. Budney, Caroline G. Wisell, Mohammad I. Habib, Cara A. Struble, Lynn Chen, Jun Liu, Melanie M. Wall, Efrat Aharonovich, Deborah S. Hasin · 发表于：Cannabis and Cannabinoid Research · 年份：2025 · DOI：10.1177/25785125251360976 · 被引用次数：3 · 研究领域：Cannabis and Cannabinoid Research、Substance Abuse Treatment and Outcomes、Forensic Toxicology and Drug Analysis

Introduction: Cannabis use has risen disproportionately among middle-aged and older U.S. adults, groups particularly vulnerable to adverse effects, including cannabis use disorder (CUD). Consumption patterns have diversified in recent years. The quantity of cannabis use, historically measured in limited ways (e.g., number of joints), is now considered a key risk factor for CUD. However, age-related differences in consumption patterns and their relationships with CUD remain understudied. This study investigated age-related differences in consumption patterns and examined the relationship between quantity of use—measured by milligrams of THC (mgTHC)—and self-reported CUD in individuals with regular cannabis use. Materials and Methods: A total of 4134 U.S. adults (ages 18+; 45.9% male, 54.1% female) who reported daily cannabis use completed an online survey assessing cannabis consumption patterns and self-reported Diagnostic and Statistical Manual of Mental Disorders , Fifth Edition’s CUD criteria. Pearson’s chi-square tests and one-way analysis of variance examined differences in sex, reasons for use, methods of consumption, CUD severity, criteria count, and mgTHC with comparisons across three age-groups (18–49, 50–64, 65+). Regression models, adjusted for sex and reasons for use, analyzed age-specific associations between mgTHC and CUD. Results: Overall, over 70% reported using cannabis for both medical and recreational purposes. Middle-aged adults were more likely to report m...