An optimized 2,2′-dipicolylamine-rutaecarpine quaternary ammonium derivative: targeting bacterial membrane disruption for enhanced anti-methicillin-resistant Staphylococcus aureus (MRSA) activity

作者：Ting Xu, Tingting Wang, Yue Tian, Xinhui Li, Yan Zhong, Jifeng Liu, Ruige Yang, Yong Guo · 发表于：European Journal of Medicinal Chemistry · 年份：2025 · DOI：10.1016/j.ejmech.2025.117975 · 被引用次数：15 · 研究领域：Antimicrobial Resistance in Staphylococcus、Cancer therapeutics and mechanisms、Antimicrobial Peptides and Activities