A novel PARP-ATR dual inhibitor exhibits anti-triple-negative breast cancer activity by inducing excessive DNA damage in the mitotic phase

作者：Chenchen Wang, Ji‐Long Duan, Nian‐Dong Mao, Miao He, Pengpeng Zhang, Yinghui Yuan, Yuan Gao, Xingrui He, Xinyi Shao, Siye Wang, Zi Hui, Hang Zhang, Ben C.B. Ko, Xiang‐Yang Ye · 发表于：Biochemical Pharmacology · 年份：2025 · DOI：10.1016/j.bcp.2025.117160 · 被引用次数：9 · 研究领域：DNA Repair Mechanisms、PARP inhibition in cancer therapy、CRISPR and Genetic Engineering