Trajectories of night light exposure and risk of overweight and obesity: a 15-year longitudinal cohort study of 218,239 Chinese children

作者：Xijie Wang, Manman Chen, Din Son Tan, Jie Hu, Bin Dong, Yu Jiang, Wannian Liang · 发表于：BMC Medicine · 年份：2025 · DOI：10.1186/s12916-025-04262-0 · 被引用次数：3 · 研究领域：Impact of Light on Environment and Health、Circadian rhythm and melatonin、Ophthalmology and Visual Impairment Studies

BACKGROUND: Light at night (LAN) is found to be associated with elevated overweight and obesity in broad population. However, evidence for the long-term LAN exposure trajectories and its influence to weight gain remained limited, especially to school-aged children who experience critical physical development. We aimed to analyze variations in body weight among children with different LAN exposure profiles, and how varying levels of LAN exposure influenced children's overweight (including obesity) risk overt time. METHODS: Children who had ≥ 5 school health examinations between 2005 and 2020 in Zhongshan were recruited in this population-based longitudinal study. LAN data of each child at each survey year were modeled with group-based trajectory model and named as sharp rise (reference; 5.5%), mild rise, high stable (69.7%), and decline. Differences of overweight incidence between groups were analyzed. RESULTS: Among 218,283 children (1,318,542 measurements; 53.1% boys; baseline mean [SE] age, 9.1 [2.5]), 12,050 (5.5%) were categorized in the sharp rise group and 152,030 (69.7%) in the stable high group. In the 189,011 participants categorized as normal or underweight at baseline, the overall incidence of overweight during follow-up was 8.80/1000 person-years (95% CI: 8.69, 8.91). Compared to the sharp rise group, the hazard ratios (HR) for developing overweight were 1.67 (95% CI: 1.28, 2.18) for boys and 1.56 (95% CI: 1.21, 2.01) for girls in stable high group, followed by th...