Mechanical Failures as Predicted by Achieving Local Versus Global T4-L1 Hip Axis Goals

作者：Karan Joseph, Tim Bui, Alexander T. Yahanda, Vivek P. Gupta, Samuel Vogl, Salim Yakdan, Jeffrey T. Galla, Miguel A. Ruiz-Cardozo, Karma Barot, Sundeep Chakladar, N. Poulin, Anurag Challagundla, Jason Ng, Anitra Krishnan, Samuel Brehm, Braeden Benedict, John C. Clohisy, Nicholas A. Pallotta, Munish C. Gupta, Brian J. Neuman, Jeffrey M. Hills, Michael P. Kelly, Daniel Hafez, Jacob K. Greenberg, Wilson Z. Ray, Camilo A. Molina · 发表于：Spine · 年份：2025 · DOI：10.1097/brs.0000000000005450 · 被引用次数：7 · 研究领域：Scoliosis diagnosis and treatment、Spine and Intervertebral Disc Pathology、Orthopaedic implants and arthroplasty

STUDY DESIGN: Retrospective cohort study. OBJECTIVE: To evaluate the predictive value of T4-L1 Hip Axis Error (HAE) and L1PA Error (L1PAE) on mechanical failure following adult spinal deformity (ASD) surgery, and to assess how error directionality and fusion length influence outcomes. SUMMARY OF BACKGROUND DATA: The T4-L1 Hip Axis is a novel framework for defining normative sagittal alignment by aligning thoracic and lumbar curvatures relative to the pelvis. Prior studies suggest that deviation from this axis may contribute to mechanical complications following ASD surgery. However, the impact of directionality, construct length, and specific risk factors remains underexplored. METHODS: A retrospective review was conducted of 271 ASD patients who underwent fusion from L2 or above to the pelvis between 2016 and 2024. T4PA and L1PA were measured from six-week postoperative standing radiographs. Alignment errors (HAE, L1PAE) were calculated based on the target threshold derived from prior normative studies. Multivariate logistic regression identified predictors of mechanical failures. Subgroup analyses were stratified by fusion length and error direction. RESULTS: HAE was a significant predictor of mechanical failure (OR=1.20 per degree, P <0.001), whereas L1PAE was not. HAE remained predictive regardless of whether patients achieved L1PA targets. In short fusions, both the signed and absolute value of HAE were associated with mechanical failure. Positive HAE (anterior T4 alignm...