Global burden of ischemic heart disease attributable to ambient and household PM2.5 exposure: a comprehensive analysis (1990–2021) from socioeconomics perspective

作者：Chenran Zhang, Wanghong Su, Hongqing Xi, Shaoru Li, Hongmei Xu, Yue Cheng, Bei Han · 发表于：Frontiers in Public Health · 年份：2025 · DOI：10.3389/fpubh.2025.1607163 · 被引用次数：2 · 研究领域：Air Quality and Health Impacts、Health, Environment, Cognitive Aging、Climate Change and Health Impacts

Objectives Socioeconomic status links to exposure of air pollutants. This study evaluates global PM 2.5 -attributable ischemic heart disease (IHD) burden from 1990 to 2021. Methods Using Global Burden of Disease (GBD) 2021 data, PM 2.5 -related IHD burdens were analyzed. Joinpoint regression identified annual percentage changes (AAPCs); Pearson correlation assessed associations with Socio-demographic Index (SDI); Slope Index of Inequality (SII) and Concentration Index (CI) were applied to quantify inequality; Frontier analysis was conducted to evaluate the efficiency of health outcomes relative to development level; Decomposition analysis was performed to identify key drivers of burden changes over time. Results From 1990 to 2021, age-standardized rates (ASMR, ASDR) of IHD attributable to ambient PM 2.5 declined to 20.85 per 100,000 (AAPC = −0.7), with attributable to household PM 2.5 decreased to 9.02 per 100,000 (AAPC = −2.49). Middle-low SDI regions exhibited the highest increases in ambient PM 2.5 -related burden, whereas high SDI regions showed marked declines (AAPC = −4.31). All regions showed downward in household PM 2.5 -attributable ASMR and ASDR. Disease burden was disproportionately higher among males and older populations. ASMR and ASDR of IHD exhibited a nonlinear association with SDI. PM 2.5 demonstrated positive correlation in regions with SDI < 0.49, and negative correlation in regions with SDI > 0.623. SII and CI indicated rising inequality in a...