Smart Nanoarchitectures for Precision RNA Delivery: Harnessing Endogenous and Exogenous Stimuli in Cancer Treatment

作者：Jintao Hao, Yue Li, Xuhui Huang, Nannan Qi, Yanan Sun, Chaoxing He, Shaokun Yang, Zhi-Yun Niu, Xian Qi, Bai Xiang · 发表于：Theranostics · 年份：2025 · DOI：10.7150/thno.112492 · 被引用次数：24 · 研究领域：RNA Interference and Gene Delivery、Advanced biosensing and bioanalysis techniques、MicroRNA in disease regulation

, pH, redox potential, enzyme, light, magnetic fields, and ultrasound), enabling targeted delivery and controlled RNA release. This review highlights recent advances in the design and mechanisms of stimuli-responsive RNA nanocarriers, emphasizing key research findings and exploring future perspectives for their clinical translation.