Understanding the gap between expectations and reality in decentralized clinical trials

作者：Yale Jiang, Ye Leng, Qing Wu, Yiru Hou, Xue–Yuan Dong, Caiwen Zeng, Dawei Wu, Hong Fang, Yu Tang, Huiyao Huang, Ning Li · 发表于：npj Digital Medicine · 年份：2025 · DOI：10.1038/s41746-025-01811-y · 被引用次数：9 · 研究领域：Health Systems, Economic Evaluations, Quality of Life、Biomedical Ethics and Regulation、Pharmaceutical Economics and Policy

Decentralized clinical trials (DCTs) have gained long-standing interest, yet their adoption as a new paradigm remains uncertain even with broader acceptance from regulatory and industry. This study aims to unveil its evolutional trend, which helps answer what the current development stage DCT is located at as well as the underlying reasons. While DCTs' prime time has not arrived, we propose solutions to advance their sustainable implementation.