Global, regional, and national epidemiology of otitis media in children from 1990 to 2021

作者：HanYu Wang, XiaoYu Zeng, Xin Miao, Bowen Yang, ShiPeng Zhang, Qinwei Fu, QinXiu Zhang, Mi Tang · 发表于：Frontiers in Pediatrics · 年份：2025 · DOI：10.3389/fped.2025.1513629 · 被引用次数：6 · 研究领域：Ear Surgery and Otitis Media、Reconstructive Facial Surgery Techniques、Hearing, Cochlea, Tinnitus, Genetics

Background: Otitis media(OM) is a prevalent ear condition, particularly among children, with a significant impact on quality of life. This study aimed to elucidate the global prevalence and disability-adjusted life years (DALYs) associated with OM in the 0-14 age group from 1990-2021, using data from the 2021 Global Burden of Disease (GBD) study. Methods: Our study conducted a comprehensive analysis of OM data from the GBD 2021 report, examining the prevalence and DALYs related to OM across 204 countries and territories over a 32-year period. Data were stratified by age, sex, year, geographic region, and sociodemographic index (SDI). Temporal trends were evaluated using estimated annual percent change (EAPC) calculations. Additionally, a global risk attribution analysis for childhood OM was conducted, and a Bayesian age-period-cohort (BAPC) model was applied to project the global burden of childhood OM from 2021-2035. Results: In 2021, the global burden of OM in children remained significant, with an incidence of 297,243,470 cases and an age-standardized prevalence of 14,775 cases per 100,000 population. OM resulted in 1,035,749 DALYs globally, with an age-standardized DALY rate of 51.48 per 100,000 population. Regionally, the highest age-standardized prevalence of OM was observed in Eastern Sub-Saharan Africa, South Asia, and Western Sub-Saharan Africa, while Central Europe, East Asia, and High-income Asia Pacific exhibited the lowest prevalence. Key risk factors identified ...