How I Do It: Three-Dimensional MR Neurography and Zero Echo Time MRI for Rendering of Peripheral Nerve and Bone

作者：Yenpo Lin, Ek T. Tan, Gracyn Campbell, Ryan Breighner, Maggie Fung, Scott W. Wolfe, John A. Carrino, Darryl B. Sneag · 发表于：Radiology · 年份：2025 · DOI：10.1148/radiol.241604 · 被引用次数：3 · 研究领域：Advanced MRI Techniques and Applications、Advanced Neuroimaging Techniques and Applications、Anatomy and Medical Technology

MR neurography sequences provide excellent nerve-to-background soft tissue contrast, whereas a zero echo time (ZTE) MRI sequence provides cortical bone contrast. By demonstrating the spatial relationship between nerves and bones, a combination of rendered three-dimensional (3D) MR neurography and ZTE sequences provides a roadmap for clinical decision-making, particularly for surgical intervention. In this article, the authors describe the method for fused rendering of peripheral nerve and bone by combining nerve and bone structures from 3D MR neurography and 3D ZTE MRI, respectively. The described method includes scanning acquisition, postprocessing that entails deep learning-based reconstruction techniques, and rendering techniques. Representative case examples demonstrate the steps and clinical use of these techniques. Challenges in nerve and bone rendering are also discussed.