Chiroptical switching and strong circularly polarized luminescence in peptide supramolecular assemblies

作者：Xin Li, Xin Li, Qingquan Han, Rui Li, Xianbao Li, Rui Li, Yutao Sang, Sen Liang, Yutao Sang, Jieling Li, Qi Li, Yajie Tian, Yang Yang, Qi Li, Shuo Bai, Junbai Li, Junbai Li · 发表于：Nature Communications · 年份：2025 · DOI：10.1038/s41467-025-61007-6 · 被引用次数：16 · 研究领域：Supramolecular Self-Assembly in Materials、Luminescence and Fluorescent Materials、Photoreceptor and optogenetics research

Peptide-based materials offer unique advantages for constructing supramolecular chiral systems due to their bioactivity and intrinsic chirality. However, precise control over the expression, transfer, and amplification of chirality from the molecular to supramolecular level remains a significant challenge in developing high-performance chiral materials. In this study, we demonstrate that achiral anions regulate hydrogen bonding interactions in dipeptide assembly, leading to the formation of chiral microrolls composed of two-dimensional nanosheets. These microrolls exhibit pH-dependent chiroptical switching and intense circularly polarized luminescence with a dissymmetry factor (|glum|) of 0.062. Furthermore, the chiral ultraviolet emission from these microrolls enables enantioselective polymerization of diacetylene, offering potential applications in chiral catalysis. These findings enhance our understanding of chirality modulation in biomolecular assemblies and provide a pathway toward the development of high-performance chiral biomaterials. Peptide-based materials offer advantages for constructing supramolecular chiral systems due to their bioactivity and intrinsic chirality but precise control over the expression, transfer, and amplification of chirality is a significant challenge. Here, the authors demonstrate that achiral anions regulate hydrogen bonding interactions in dipeptide assembly, leading to the formation of chiral microrolls composed of 2D nanosheets.