Precision medicine: Crossing the biomedical scales with AI

作者：Sharat Israni, Gary D. Bader, Sergio E. Baranzini, John A. Capra, Marina Sirota, Christina V. Theodoris, Chun Ye · 发表于：The Journal of Precision Medicine Health and Disease · 年份：2025 · DOI：10.1016/j.premed.2025.100010 · 被引用次数：3 · 研究领域：Health, Environment, Cognitive Aging、Machine Learning in Healthcare、Biomedical and Engineering Education

Precision Medicine, targeted for each person, has presented a major challenge in scaling up to wide use. Reflecting the true behavior of the human body, it requires inquiry across the biomedical scales, from the genome all the way up to the environmental factors impinging on that person. In computation terms, this is a problem of unprecedented complexity. With AI showing its potential, the thoughtful application of advanced machine intelligence, knowledge networks, machine reasoning power and new computational paradigms—guided by human oversight at every stage—can help unlock major advances in treatment and prevention.