Key elements of follow-up care after acute pulmonary embolism focusing on long-term sequelae: a Delphi study among European experts

作者：R. Mali, M.K. Ninaber, Thijs E. van Mens, Stavros Konstantinides, F A Klok, Delphi Study Contributing Group, George Giannakoulas, Marcin Kurzyna, Marco Zuin, Konstantinos Dimopoulos, Jean Luc Vachiery, Lukas Hobohm, Roberto Badagliacca, Anton Vonk Noordegraaf, Laurent Bertoletti, Luis Jose Jara-Palomares, Olivier Sitbon, Marc Humbert, Silvia Ulrich, Josien van Es, Coen van Kan, Maarten Ninaber, Harm-Jan Bogaard, Esther Nossent, Bas Langeveld, Ivo van der Lee, Ager Andersen, Joanna Pepke Zaba, Dieuwke Luijten, Francis Couturaud, Cecile Tromeur, Olivier Sanchez, Luca Valerio, Menno Huisman, Nick van Es, Cihan Ay, Cecilia Becattini, Irene Lang, Walter Ageno, Melanie Ferreira, Fionnuala Ni Ainle, Roberto Pola, Lilian Meijboom, Lucia Kroft, Karen Sheares · 发表于：European Heart Journal - Quality of Care and Clinical Outcomes · 年份：2025 · DOI：10.1093/ehjqcco/qcaf053 · 被引用次数：7 · 研究领域：Venous Thromboembolism Diagnosis and Management、Pulmonary Hypertension Research and Treatments、Chronic Obstructive Pulmonary Disease (COPD) Research

AIMS: A considerable proportion of patients develop long-term sequelae after an acute pulmonary embolism (PE). Beyond chronic thrombo-embolic pulmonary hypertension (CTEPH), current guidelines provide limited guidance regarding a structured approach for assessment and management of these patients. This study aimed to establish a framework of multidisciplinary follow-up care of PE-survivors. METHODS AND RESULTS: A Delphi study was conducted among a multidisciplinary panel of PE specialists from across Europe to gather expert opinions, and where possible reach consensus, on key aspects of PE follow-up care. Two rounds of surveys were distributed among 45 venous thromboembolism (VTE) experts, with 39 completing both rounds. Consensus was reached that follow-up of PE survivors should address the entire spectrum of post-PE sequelae, i.e. CTEPH, chronic thromboembolic pulmonary disease, but also all other presentations of the post-PE syndrome. Routine assessment at 3 months should involve patient-reported outcome measures, including quality of life. A single, uniform protocol was preferred over locally adapted approaches. Earlier follow-up, prior to the 3-month mark, to detect post-PE sequelae was not considered necessary for most patient subgroups. Right heart catheterization to confirm CTEPH should be reserved for specialized pulmonary hypertension centres, while other diagnostic modalities such as computed tomography, V/Q scan, cardiopulmonary exercise testing and transthoracic ...