Profiling antigen-binding affinity of B cell repertoires in tumors by deep learning predicts immune-checkpoint inhibitor treatment outcomes

作者：Bing Song, Kaiwen Wang, Saiyang Na, Jia Yao, Farjana Fattah, Alexandra Martin, Mitchell S. von Itzstein, Donghan M. Yang, Jialiang Liu, Yaming Xue, Chaoying Liang, Yuzhi Guo, Indu Raman, Chengsong Zhu, Jonathan E. Dowell, Jade Homsi, Sawsan Rashdan, Shengjie Yang, Mary Gwin, Tuoqi Wu, David Hsiehchen, Yvonne Gloria-McCutchen, Ping Lu, Prithvi Raj, Xiao‐chen Bai, Jun Wang, José R. Conejo-García, Yang Xie, Junzhou Huang, David E. Gerber, Tao Wang · 发表于：Nature Cancer · 年份：2025 · DOI：10.1038/s43018-025-01001-5 · 被引用次数：5 · 研究领域：Cancer Immunotherapy and Biomarkers、Immunotherapy and Immune Responses、vaccines and immunoinformatics approaches