Epidemiological characteristics and spatial clustering analysis of human brucellosis in Zibo City, Shandong Province, China, 2006–2024

作者：Rongtao Zhao, Ruixuan Sun, Feng Zhang · 发表于：Frontiers in Public Health · 年份：2025 · DOI：10.3389/fpubh.2025.1580265 · 被引用次数：6 · 研究领域：Brucella: diagnosis, epidemiology, treatment、Zoonotic diseases and public health、Parasitic Diseases Research and Treatment

Background: The significant rise in human brucellosis incidence is a serious public health issue in Zibo City. However, its temporal and spatial distribution has not been thoroughly investigated. Objective: This study aims to describe the demographic, temporal, and spatial distribution patterns and clustering characteristics of human brucellosis cases in Zibo City from 2006 to 2024, in order to develop and implement effective scientific prevention and control strategies. Methods: Case data were obtained from the Infectious Disease Surveillance System of the Chinese Disease Control and Prevention Information System. The epidemiological characteristics and spatial aggregation of human brucellosis were analyzed using descriptive analysis and spatial autocorrelation analysis. The incidence of brucellosis in 2025 was predicted using an ARIMA model. Results: Data on human brucellosis cases in Zibo City from 2006 to 2024 were obtained from the national infectious disease reporting information management system. Spatial autocorrelation analysis and temporal-spatial scan statistics were used to identify potential changes in the temporal-spatial distribution of human brucellosis in Zibo City. From 2006 to 2021, a total of 2,176 brucellosis cases were reported in Zibo City, with an average annual incidence rate of 2.50 per 100,000. Middle-aged and older adult populations (aged 35-74 years) were the primary affected groups, accounting for 86.76% (1,888/2,176) of all reported cases. The i...