Determinants of cervical cancer screening utilisation among women in the least developed countries: A systematic review and meta-analysis

作者：Tika Rana, Dorothy Ngo Sheung Chan, Bernard M. H. Law, Kai Chow Choi, Sunil Shrestha, Winnie K.W. So · 发表于：PLoS ONE · 年份：2025 · DOI：10.1371/journal.pone.0321627 · 被引用次数：6 · 研究领域：Cervical Cancer and HPV Research、Global Cancer Incidence and Screening、Endometrial and Cervical Cancer Treatments

BACKGROUND AND AIMS: Globally, cervical cancer is the fourth most common cancer among women, and more than 90% of all cervical cancer-related deaths worldwide are recorded in resource-limited countries. The present review investigated the uptake rate of cervical cancer screening and identified the factors associated with screening service utilisation in the female populations of least developed countries (LDCs). METHODS: Five electronic databases (EMBASE, Ovid MEDLINE, CINAHL, Cochrane Library, and PubMed) and grey literature were searched for relevant literature using the keywords of the included studies. Both qualitative and quantitative studies were included. Three reviewers performed critical appraisals using the Mixed Methods Appraisal Tool. Meta-analysis was performed to pool the quantitative results from comparable studies. RESULTS: A total of twenty-five studies were included in the review. The cervical cancer screening uptake rate in LDCs ranged from 4% to 21%. Multiple factors were associated with screening service utilisation among women in the LDCs, namely socio-demographic characteristics, including employment status (odds ratio (OR): 2.72; 95% CI: 1.97-3.76; p < 0.001); knowledge of cervical cancer and its screening (OR: 3.39; 95% CI: 2.00-5.75; p < 0.001); sexual and reproductive health-related factors such as parity status (OR: 2.73; 95% CI: 1.61-4.64; p = 0.002); healthcare providers' recommendations (OR: 5.32; 95% CI: 2.44-11.58; p < 0.001); perceived risk o...