Prevalence of Tuberculosis among migrants under national screening programs: a systematic review and meta-analysis

作者：Qin Chen, Ningjun Ren, Shengya Liu, Zixin Qian, Mengdie Li, Aliyu Mustapha, Wei Luo, Jinghua Li, Wenxi Wang, Chun Hao · 发表于：Global Health Research and Policy · 年份：2025 · DOI：10.1186/s41256-025-00424-y · 被引用次数：6 · 研究领域：Tuberculosis Research and Epidemiology、Migration, Health and Trauma、Parasites and Host Interactions

BACKGROUND: Tuberculosis (TB) continues to pose a significant global public health threat, particularly among migrant populations. Screening policies exist in many receiving countries but differ markedly, and there is limited pooled evidence on TB and latent TB infection (LTBI) prevalence among migrants under different screening frameworks. This systematic review and meta-analysis aims to synthesize TB and LTBI prevalence among migrants and compared national screening policies to inform evidence-based public health planning. METHODS: PubMed, Embase, Web of Science and Cochrane Library were searched for studies published 2016-2023. Random-effects models generated pooled prevalence estimates with 95% CIs; subgroup analyses examined differences by screening stage, migrant category, and country-of-origin incidence. Sensitivity analyses tested robustness. Government and health-agency websites were systematically examined and scored to table national TB-screening requirements. RESULTS: 36 studies (26 TB, 21 LTBI) covering 40,738,331 migrants screened met inclusion criteria. The Pooled TB prevalence was 214.52/100,000 (95% CI 112.18-349.66) and LTBI prevalence 14.9% (95% CI 9.91-20.60). Countries employing both pre-entry screening and subsequent post-entry surveillance achieved the lowest TB prevalence (94.09/100,000). The highest burdens occurred among refugees/asylum seekers (439.25/100,000) and migrants from countries with TB incidence 300-499/100,000 (491.96/100,000). LTBI was m...