Comorbidity and temporal associations between mental disorders among college students in the world mental health international college student initiative

作者：Annelieke M. Roest, Ymkje Anna de Vries, Julia R Pozuelo, Maria Petukhova, Sue Lee, Nancy A. Sampson, Yesica Albor, Ahmad N. AlHadi, Jordi Alonso, Nouf Al-Saud, Yasmin Altwaijri, Claes Andersson, Lukoye Atwoli, Randy P. Auerbach, Caroline Ayuya Muaka, Patricia M Báez-Mansur, Laura Ballester, Jason Bantjes, Harald Baumeister, Marcus Bendtsen, Corina Benjet, Anne H. Berman, Ronny Bruffaerts, Paula Carrasco, Silver C N Chan, Irina Cohut, María Anabell Covarrubias Díaz Couder, Marcelo A. Crockett, Pim Cuijpers, Daniel David, Dong Dong, David Daniel Ebert, Jorge Gaete, Carlos G. Forero, Margalida Gili, Raúl A. Gutiérrez–García, Josep María Haro, Penelope Hasking, Xanthe Hunt, Mathilde M. Husky, Florence Jaguga, Álvaro I. Langer, Irene Léniz, Yan Liu, Scarlett Mac‐Ginty, Vania Martínez, Margaret McLafferty, Andrea Miranda, Iris Rubí Monroy Velasco, Elaine Murray, Catherine Mawia Musyoka, Cătălin Nedelcea, Daniel Núñez, Siobhan O’Neill, José A. Piqueras, Codruța Alina Popescu, Ana Paula Prescivalli, Charlene Rapsey, Kealagh Robinson, Tíscar Rodríguez‐Jiménez, Wylene Saal, Oi Ling Siu, Dan J. Stein, Sascha Y. Struijs, Cristina Tomoiagă, Karla Patricia Valdés‐García, Eunice Vargas‐Contreras, Daniel Vigo, Angel Y Wang, Samuel Yeung Shan Wong, Ronald C. Kessler, Marilisa Boffo, Guilherme Borges, Elsie Breet, Paula Cristóbal-Narvaez, Sergio Cruz-Hernández, Nadia Garnefski, Praxedis Cristina Hernández Uribe, Petra Hurks, Karen Jacobs, Leontien Jansen, Ana Lucía Jiménez-Pérez, Elisabeth F. Klinkenberg, Vivian Kraaij, Rodrigo Antunes Lima, Christine Lochner, Francisca Ongecha Owuor, Maria Elena Medina-Mora, Tiana Mori, Lonna Munro, Richard J. Munthali, Jessica Nooij, Maria Abigail Paz-Peréz, Marisa Rebagliato, Danielle Remmerswaal, Miquel Roca, Elske Salemink, Claudia van der Heijde, Wouter Voorspoels, Reinout W. Wiers · 发表于：Psychiatry Research · 年份：2025 · DOI：10.1016/j.psychres.2025.116605 · 被引用次数：6 · 研究领域：Mental Health Treatment and Access、Personality Disorders and Psychopathology、Child and Adolescent Psychosocial and Emotional Development

BACKGROUND: Mental disorders are highly prevalent among students worldwide. This study aims to examine comorbidity and temporal associations between mental disorders among students. METHODS: The study included 72,288 students from 18 countries as part of the World Mental Health International College Student (WMH-ICS) Initiative, with cross-sectional data collected between 2017 and 2023. Screening for common DSM-5 disorders was conducted using validated screening measures. Latent variables were examined using exploratory principal axis factor analysis on a correlation matrix among the lifetime mental disorders. Based on age-of-onset information, multivariable poisson regression models were used to examine associations of prior disorders with the first onset of other disorders. RESULTS: 27.0 % of students screened positive for only one lifetime disorder, 17.1 % for two, 10.9 % for three, and 10.6 % for 4+ disorders. In the factor analysis, three latent variables were found, comprising: internalizing disorders (generalized anxiety disorder, major depressive episode, post-traumatic stress disorder, and panic disorder), substance use disorders (drug use disorder and alcohol use disorder), and externalizing disorders (attention deficit/hyperactivity disorder and mania/hypomania). Prior internalizing and externalizing disorders were associated with the subsequent first onset of all other disorders with risk ratios ranging from 1.5-7.5. Substance use disorders were less consistently ...