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[Study on transmission characteristics and genetic variation of carbapenem-resistant Klebsiella pneumonia based on whole genome sequencing].

作者:J. C. Li, Yulu Chen, Y L Ge, J R Hu, Xiaofei Du, Jinyuan Liu, H Xing, Pei Gao, X Han, Y L Li, Yongmei Tang, Jia Li, Zhi Gang Cui, Jianghong Zhang, Haijian Zhou, A Y Dong · 发表于:PubMed · 年份:2025 · DOI:10.3760/cma.j.cn112150-20241216-01011 · 被引用次数:1 · 研究领域:Antibiotic Resistance in Bacteria、Antibiotics Pharmacokinetics and Efficacy、Bacterial Identification and Susceptibility Testing

The popular strain in the hospital of CRKP is a KPC-2_ST11 clone group carrying iucA, rmpA/rmpA2, with cross-department transmission and mutation. ST5492 is a newly-launched clone type. The intensive care unit of hvKP carrying five virulence genes, including peg-344, should be alert to the epidemic risk of CR-hvKP outbreak.