Current Concepts on Imaging and Artificial Intelligence of Osteosarcopenia in the Aging Spine: A Review for Spinal Surgeons by the SRS Adult Spinal Deformity Task Force on Senescence

作者：Corey T. Walker, Robin Babadjouni, Wende N. Gibbs, Elizabeth L. Lord, Adeesya Gausper, Joseph A. Osorio, Camilo Molina, Kristen E. Jones, Miranda L. van Hooff, Alexander A. Theologis, Mitsuru Yagi, Laurel C. Blakemore, Suken A. Shah, Serena S. Hu, Marinus de Kleuver, Javier Pizones, Michael P. Kelly, Ferrán Pellisé, Christopher P. Ames, Robert K. Eastlack · 发表于：Spine · 年份：2025 · DOI：10.1097/brs.0000000000005426 · 被引用次数：3 · 研究领域：Scoliosis diagnosis and treatment、Bone health and osteoporosis research、Radiomics and Machine Learning in Medical Imaging

STUDY DESIGN: Narrative review. OBJECTIVE: To explore the intersection of osteoporosis, sarcopenia, radiomics, and machine learning in spine surgery, with a focus on clinical applications and opportunities for advancing assessment and predictive modeling methods. SUMMARY OF BACKGROUND DATA: Osteoporosis and sarcopenia are significant contributors to negative outcomes in the aging adult spine. Current methodologies for evaluating these disease states remain limited, with significant variability and poor standardization. Advances in computational medicine provide a novel opportunity to improve quantitative assessment of osteosarcopenia, as demonstrated in other areas of medicine. Using radiomic approaches for predictive outcome modeling in spine surgery remains largely untapped. MATERIALS AND METHODS: A comprehensive literature search was performed. Articles were identified using the search terms "osteoporosis," "sarcopenia," "osteosarcopenia," "radiomics," "spine surgery," and "machine learning." Relevant studies were selected based on their focus on the intersection of these topics, emphasizing clinical, imaging, and computational methodologies in spine surgery. RESULTS: This review highlights the existing conventional and research methods of assessing both osteoporosis and sarcopenia, particularly regarding their clinical application in spine surgery. Areas of research within the radiomic space for both conditions are also discussed to describe opportunities for growth of fu...