HIV, STI, and Hepatitis Among People Who Inject Drugs at a Sexual Health Clinic in Melbourne, Australia: 2012 to 2022

作者：Tiffany R. Phillips, Esha Abraham, Christopher K Fairley, Rayner Kay Jin Tan, Ei T. Aung, Jason J. Ong, Eric P. F. Chow · 发表于：Open Forum Infectious Diseases · 年份：2025 · DOI：10.1093/ofid/ofaf339 · 被引用次数：1 · 研究领域：HIV, Drug Use, Sexual Risk、HIV/AIDS Research and Interventions、Sex work and related issues

Abstract Background This study aimed to examine the sexual practices and sexually transmitted infection (STI) positivity among people who inject drugs (PWID). Methods This was a repeated cross-sectional study analyzing data collected at a sexual health center during 2012–2022. New clients who were aged 18 and older, sexually active, and had injected drugs in the last 12 months were eligible for inclusion. Clients were categorized as men who have sex with women only (MSWO), gay or bisexual men who have sex with men (gbMSM), or women. We calculated the 2-year positivity of HIV, STIs, hepatitis B virus (HBV), and hepatitis C virus (HCV), and temporal analyses were conducted using the chi-square trend test. Results A total of 1229 clients (395 MSWO, 457 gbMSM, and 377 women) were included in the study. There was a significant rise in syphilis (Ptrend = .0033); however, no significant changes were observed for other infections. The 2-year positivity for syphilis increased significantly from 0.6% (1/156) in 2012/2013 to 10.0% (13/130) in 2020/2021 (Ptrend = .0033). gbMSM had higher positivity for any infection (29.1%, 133/457) than MSWO (19.8%, 78/395) and women (17.0%, 64/377; P < .001). Positivity of new HIV was 2.6% (95% CI, 1.6%–3.8%; 22/861), infectious syphilis was 6.8% (95% CI, 5.2%–8.7%; 59/866), gonorrhea was 8.6% (95% CI, 6.8%–10.7%; 77/892), chlamydia was 8.7% (95% CI, 7.0%–10.5%; 95/1093), HBV was 0.6% (95% CI, 0.1%–1.6%; 3/545), and HCV antibody was 10.0% (95% C...