Multi-cohort validation of a lipid metabolism and ferroptosis-associated index for prognosis and immunotherapy response prediction in hormone receptor-positive breast cancer

作者：Cheng Zeng, Jiani Wang, Shen Zhao, Yuhan Wei, Yalong Qi, Shuning Liu, Yuanyi Wang, Hewei Ge, Xiaoqi Yang, Yujing Tan, Yi-Zhou Jiang, Haili Qian, Fei Ma · 发表于：International Journal of Biological Sciences · 年份：2025 · DOI：10.7150/ijbs.113213 · 被引用次数：14 · 研究领域：Ferroptosis and cancer prognosis、Cancer, Lipids, and Metabolism、RNA modifications and cancer

This study identified distinct LMF-related molecular clusters in HR+ breast cancer with unique prognostic and immune characteristics. The LMF_index shows potential as a prognostic biomarker and a guide for immunotherapy strategies in HR+ breast cancer.