DiffuSETS: 12-Lead ECG generation conditioned on clinical text reports and patient-specific information

作者：Yongfan Lai, Jiabo Chen, Qinghao Zhao, Deyun Zhang, Yue Wang, Shijia Geng, Hongyan Li, Shenda Hong · 发表于：Patterns · 年份：2025 · DOI：10.1016/j.patter.2025.101291 · 被引用次数：7 · 研究领域：ECG Monitoring and Analysis、EEG and Brain-Computer Interfaces、Phonocardiography and Auscultation Techniques

The scarcity of high-quality electrocardiogram (ECG) data, driven by privacy concerns and limited medical resources, creates a pressing need for effective ECG signal generation. Existing approaches for generating ECG signals typically rely on small training datasets, lack comprehensive evaluation frameworks, and overlook potential applications beyond data augmentation. To address these challenges, we propose DiffuSETS, a framework capable of generating ECG signals with high semantic alignment and fidelity. DiffuSETS accepts various modalities of clinical text reports and patient-specific information as inputs, enabling the creation of clinically meaningful ECG signals. Additionally, we introduce a comprehensive benchmarking methodology to assess the effectiveness of ECG generative models. Our model achieves excellent results in tests, proving its superiority in the task of ECG generation. Furthermore, we showcase its potential to mitigate data scarcity while exploring applications in cardiology education and medical knowledge discovery.