Blocking TRPM4 alleviates pancreatic acinar cell damage via an NMDA receptor-dependent pathway in acute pancreatitis

作者：Yifan Ren, Qing Cui, Wuming Liu, Hangcheng Liu, Tao Wang, Hongwei Lu, Yi Lv, Rongqian Wu · 发表于：Theranostics · 年份：2025 · DOI：10.7150/thno.116520 · 被引用次数：4 · 研究领域：Pancreatitis Pathology and Treatment、Apelin-related biomedical research

TRPM4 activation contributes to pancreatic acinar cells damage via an NMDAs-dependent pathway in AP. The TRPM4/NMDARs complex provides a new target for the future treatment of AP.