Prevalence of Myopia and Axial Length Distribution in China: The Wuhu Children and Adolescents Eye Study

作者：Li Dong, Wen‐Da Zhou, Yabin Hu, Wei Li, Wei Cao, Ning-Hong Chen, Di Liu, Cheng Zhen, Yu-Chun Zheng, Jost B. Jonas, Wenbin Wei · 发表于：Investigative Ophthalmology & Visual Science · 年份：2025 · DOI：10.1167/iovs.66.6.33 · 被引用次数：11 · 研究领域：Ophthalmology and Visual Impairment Studies、Glaucoma and retinal disorders、Retinopathy of Prematurity Studies

Purpose: To re-assess myopia prevalence, update the database of ocular biometric parameters, and assess the prevalence of fundus abnormalities in schoolchildren and adolescents in Wuhu, Anhui Province, China. Methods: The Wuhu Children and Adolescents Eye Study (WCAES) is a longitudinal population-based cohort study, and the cross-sectional analysis results of the baseline assessment are reported here. It included 315,569 out of 330,173 eligible children and adolescents (95.6%), ages 2 to 19 years, from 513 schools with measurements of presenting distance visual acuity (PDVA) and uncorrected distance visual acuity (UDVA), non-cycloplegic autorefractometry, ocular biometry, and color fundus photography. Fundus abnormalities were assessed by an artificial intelligence-based system. Results: Prevalences of likely myopia (-1.00 D < refractive error ≤ -0.50 D), myopia (refractive error ≤-1.00 D), low myopia (-3.00 D < refractive error ≤ -1.00 D), moderate myopia (-6.00 D < refractive error ≤ -3.00 D), and high myopia (refractive error ≤ -6.00 D) were 13.58% (95% confidence interval [CI], 13.46-13.70), 56.92% (95% CI, 56.74-57.10), 32.87% (95% CI, 32.70-33.04), 19.74% (95% CI, 19.60-19.88), and 4.31% (95% CI, 4.24-4.38), respectively. Among high-school students, myopia prevalence was 92.18% (95% CI, 91.68-92.68). High myopia prevalence rates in kindergarten, elementary, middle, and high schools were 0.30% (95% CI, 0.18-0.43), 1.53% (95% CI, 1.48-1.59), 9.05% (95% CI, 8.86-9.24), an...