Evaluating dietary quality and dietary inflammatory potential in cognitive impairment patients in China

作者：Dongsheng Bian, Furu Liang, Yong You, Xianfeng Li, Hua Hu, Huali Wang, Huayan Liu, Lu Shen, Oumei Cheng, Qiumin Qu, Shunliang Xu, Weihong Kuang, Qinying Ma, Xiaoping Pan, Xinyu Zhao, Yang Zhang, Yifeng Du, Ying Xu, Yongan Sun, Zhengluan Liao, Jintao Wang, Jianping Li, Jinwen Xiao, Haixia Li, Xinyi Xie, Zhenyu Yun, Jieli Geng, Wenwei Cao, Nan Zhi, Ru‐Jing Ren, Hengge Xie, Gang Wang, representing ADC · 发表于：Alzheimer s & Dementia · 年份：2025 · DOI：10.1002/alz.70345 · 被引用次数：3 · 研究领域：Nutritional Studies and Diet、Nutrition and Health in Aging、Dementia and Cognitive Impairment Research

INTRODUCTION: Diet plays a critical role in the prevention and treatment of cognitive impairment, yet dietary intake in patients with cognitive impairment in China remains insufficiently studied. METHODS: A 25-item semi-quantitative food frequency questionnaire was used in a national online survey in China. The Dietary Inflammatory Index was calculated, and principal component analysis was used to identify dietary patterns. RESULTS: The average daily energy intake was 1131.59 ± 486.30 kcal, below recommended levels. Patients in the pro-inflammatory diet group had lower intakes of nutrients than those in the anti-inflammatory group. Ordinal logistic regression indicated that adherence to a high-quality protein dietary pattern was associated with lower cognitive impairment severity, whereas the high cereal and snack dietary pattern was associated with increased severity. CONCLUSION: Inadequate intake of essential nutrients, particularly energy and protein, exacerbates cognitive decline. Promoting high-quality protein intake while reducing low-quality carbohydrates may mitigate cognitive deterioration and improve patient health outcomes. HIGHLIGHTS: Cognitive impairment patients in China show significantly low intake of energy, protein, and essential nutrients, which contributes to malnutrition and exacerbates cognitive decline. The study finds a link between inadequate nutrient intake and increased dietary inflammatory potential, which may accelerate cognitive decline. The pro-...