Efficacy and hepatotoxicity of tamoxifen-loaded fructose-based nanodrug for breast cancer treatment

作者：Mingliang Fan, Jiayu Zheng, Yue Huang, Hongxu Lu, Mingxia Lu · 发表于：Journal of Materials Chemistry B · 年份：2025 · DOI：10.1039/d5tb00468c · 被引用次数：5 · 研究领域：Nanoparticle-Based Drug Delivery、Graphene and Nanomaterials Applications、Curcumin's Biomedical Applications

) of nanodrugs could inhibit cellular proliferation of breast cancer cells significantly without showing obvious toxicity to liver organoids, implicating a favorable efficacy and safety profile of these nanodrugs. Therefore, the tamoxifen-loaded fructose-based nanodrug might be a promising platform for improving tumor targeting and reducing side effects in breast cancer treatment.