Association between sarcopenic obesity and dementia in the Chinese elderly using different definitions of obesity: evidence from the CHARLS

作者：Lang Peng, Qingwei Xiang, Ge Jia, Renyi Yin · 发表于：Frontiers in Aging Neuroscience · 年份：2025 · DOI：10.3389/fnagi.2025.1540272 · 被引用次数：11 · 研究领域：Nutrition and Health in Aging、Frailty in Older Adults、Body Composition Measurement Techniques

Objectives: The prevalence of sarcopenic obesity, characterized by the coexistence of reduced muscle mass and function alongside increased adipose tissue, is increasing in the aging population. This study aims to investigate the association between sarcopenic obesity and dementia risk in community-dwelling older adults in China, utilizing a nationally representative dataset. Furthermore, we aim to assess the comparative effectiveness of waist circumference versus body mass index as indicators for assessing this risk association. Design: The study was designed as a cross-sectional study. Setting and participants: Based on the nationally representative data from the China Health and Retirement Longitudinal Study (CHARLS) 2015, a total of 5,320 community-dwelling participants aged 60 years and above were categorized into four groups according to their respective classifications of normal status, possible sarcopenia, obesity, and sarcopenic obesity. Methods: Multivariable logistic regression models were used to analyze the relationship between sarcopenic obesity and probable dementia while adjusting for potential confounders. Results: 1.325-2.479) were significantly associated with an increased risk of probable dementia. In contrast, abdominal obesity alone, defined by waist circumference (WC), was not significantly associated with dementia risk. When stratified by age and gender, the association between sarcopenic obesity and probable dementia remained significant. Conclusion an...