Targeting the BCKDK/BCLAF1/MYC/HK2 axis to alter aerobic glycolysis and overcome Trametinib resistance in lung cancer

作者：Hao Wu, Jiajia Yang, Zixia Yang, Yan Xiao, Ran Liu, Jing Jia, Xinrui Zhang, Yuting Zhang, Zheng Fu, Zhi Yao, Junqiang Lv · 发表于：Cell Death and Differentiation · 年份：2025 · DOI：10.1038/s41418-025-01531-6 · 被引用次数：14 · 研究领域：Cancer, Hypoxia, and Metabolism、Epigenetics and DNA Methylation、RNA modifications and cancer