Probiotics in the Management of Microplastics-Induced Enteritis

作者：Xilong Deng, Xia Sheng, Lingtong Meng, Yanan Li, Jingpeng Yang · 发表于：Food Reviews International · 年份：2025 · DOI：10.1080/87559129.2025.2511908 · 被引用次数：3 · 研究领域：Microplastics and Plastic Pollution、Recycling and Waste Management Techniques、biodegradable polymer synthesis and properties

Given the extensive utilization of microplastics in the food industry, there is a growing prominence of health issues they induce, particularly gut infections. Incorporating probiotics may serve as an effective strategy for addressing this inflammation and infection. Here, we provide an overview of current applications of probiotics in promoting gut well-being along with their principal modes of action. Furthermore, we explore the potential role of probiotics in mitigating or aiding in the treatment of microplastic-induced gut inflammation. Our investigation reveals that probiotics can exert a positive regulatory role by mitigating oxidative stress in the gut, modulating immune responses effectively while reducing neurotoxicity. We further investigate the mechanisms by which probiotics alleviate or assist in the treatment of microplastic-associated enteritis, encompassing 1) regulation of gut microbiota composition; 2) enhancement of gut mucosal barrier function; 3) modulation of gut immune balance; and 4) promotion of microplastic excretion and degradation. Future research should focus on exploring specific probiotic strains, combinations of single and mixed bacteria, colonization capacity, optimal dosage regimens, as well as long-term safety profiles. Additionally, further investigation into the mechanism underlying probiotic action in microplastic-induced enteritis is warranted to provide scientific guidance for future research and development of probiotic formulations.