Serum Dechlorane Plus (DPs) levels in thyroid disease patients: Influence of gender, age, and metastasis

作者：Ye Wu, Yuhao Fan, Xinyu Lou, Dan Chen, Jun Jin, Ying Wang, Ting Yang, Zhiyan Liu · 发表于：Ecotoxicology and Environmental Safety · 年份：2025 · DOI：10.1016/j.ecoenv.2025.118410 · 被引用次数：1 · 研究领域：Cancer, Hypoxia, and Metabolism、Bone health and treatments、Thyroid Cancer Diagnosis and Treatment

The study revealed that the serum DPs concentrations in thyroid patients ranged from 2.45 to 141.25 ng/g lw, with the female group showing higher DPs concentrations and a higher f anti value than males. Younger participants exhibited had higher serum DPs concentrations and f anti values compared to older age groups, compared to middle-aged and elderly groups, indicating a tendency for anti-DP accumulation. In addition, the f anti value was found to be lower in patients with metastatic thyroid tumor, potentially due to an enhanced capacity to metabolize anti-DP post-metastasis. We also examined the population of patients with varying diameters. Consequently, future studies should further investigate the possible relationship between DPs and thyroid function, with an emphasis on anti-DP.