Liver protection of CACA technical guidelines for holistic integrative management of cancer

作者：Ningning Zhang, Lungen Lu, Baoshan Cao, Yanjing Gao, Feng Han, Liangping Li, QiJiong Li, Shu Li, Xiaowu Li, Jingfeng Liu, Yefu Liu, Yingqian Lv, Yongzhan Nie, Xizhong Shen, Dongde Wu, Qiang Wu, Jun Xu, Liping Yao, Ning Zhang, Yuzheng Zhuge, Xiu-Bao Ren, Dean Tian, Guohong Han, Wei Lu, Yan Bai, Haining Fan Xiaobing Chen, Yingbin Hu, Weidong Jia, Zuoyi Jiao, Yongdong Jin, Duo Li, Runmei Li, Wenxin Li, Xiangcheng Li, Yue Li, Zhiwei Li, Jing Liang, T.‐S. LIN, Taotao Liu, Liang Ma, Jincheng Meng, Tao Peng, Chengyi Sun, Zhiqiang Sun, Hongwei Wang, Lu Wang, Shunxiang Wang, Yusheng Wang, Xiaoyong Wei, Limin Xia, Yijun Xia, Qing Xie, Tao Xin, Jianhua Xu, Liang Xu, Qi Xu, Dong Yan, Changqing Yang, Jin‐Hui Yang, Jianhua Yi, Yongxiang Yi, Lan Yu, Songning Yu, Liaoyun Zhang, Yue Zhao, Hong Zhu, Hui Zhuang · 发表于：Holistic Integrative Oncology · 年份：2025 · DOI：10.1007/s44178-025-00157-5 · 被引用次数：3 · 研究领域：Colorectal Cancer Treatments and Studies、Lung Cancer Treatments and Mutations、Hepatocellular Carcinoma Treatment and Prognosis

Abstract Background Antitumor drugs (such as chemotherapy, targeted therapy, immunotherapy, etc.) and local treatments like surgery and radiotherapy are widely used in cancer treatment, but they often carry the risk of liver injury, which seriously affects the prognosis and quality of life of patients. Therefore, liver protection is of crucial importance in cancer treatment. Methods Relevant experts organized by the Oncology Hepatology Committee of China Anti-Cancer Association Association formulated this guideline based on the latest research achievements and clinical practice experience at home and abroad, aiming to provide comprehensive and systematic guidance for clinicians on liver protection. Results This guideline elaborates on the importance of liver protection during cancer treatment, comprehensively introduces the pathophysiological mechanisms, diagnosis, treatment, and preventive measures of antitumor treatment-related liver injury. Conclusion This guideline is helpful for clinicians to formulate individualized treatment plans, improve the treatment outcome and quality of life of cancer patients, and provides an important reference for the clinical practice of liver protection in cancer treatment.