Demographic and clinical characteristics of children and adolescents with headache and/or dizziness and hemodynamic responses to head-up tilt test

作者：Runmei Zou, Shuo Wang, Fang Li, Ping Liu, Donglei Liao, Liqun Liu, Jing Liu, Hong Cai, Yuwen Wang, Cheng Wang · 发表于：˜The œItalian Journal of Pediatrics/Italian journal of pediatrics · 年份：2025 · DOI：10.1186/s13052-025-01976-y · 被引用次数：2 · 研究领域：Cardiovascular Syncope and Autonomic Disorders、Vestibular and auditory disorders、Neuroscience of respiration and sleep

BACKGROUND: Headache and dizziness are common symptoms in children and adolescents, but the causes of headache/dizziness in most pediatric patients are not clearly defined. We intended to investigate the demographic and clinical features of pediatric patients with headache and/or dizziness and responses to head-up tilt test (HUTT). METHODS: The demographic data and medical records of children and adolescents, with a primary complaint of headache and/or dizziness and undergoing HUTT between January 2001 and June 2023, were retrospectively reviewed and analyzed. Children and adolescents with headache and/or dizziness secondary to fever, trauma, or other obvious etiology were excluded. For those with positive responses to HUTT, the symptom score and HUTT responses were collected after treatment at follow-up. RESULTS: Among 2709 patients with unexplained headache and/or dizziness, 1080 (39.87%) cases presented positive responses to HUTT, whereas 1629 (60.13%) cases had negative responses. Among patients with positive responses, 930 (34.33%) cases presented a response of vasovagal syncope, 143 (5.28%) cases of postural orthostatic tachycardia syndrome, and 7 (0.26%) cases of orthostatic hypertension. Multivariate Logistic regression analysis demonstrated that females, older age, and low body mass index percentile increased the risk of being positive responses. At follow-up, HUTT results of 236 patients were collected, among which 131 (55.51%) cases turned negative HUTT responses a...