Normative range of MRI ‐based fetal body volume and association with ultrasonographically estimated fetal weight at 16–36 weeks: prospective study

作者：Amine Bouachba, Raphaël Bartin, J. De Jesus Neves, L. Bussières, D. Grévent, J. Virfollet, G. Gauchard, L. Bobet, N. Roux, Benjamin Glémain, Laurent Salomon, G. Gorincour · 发表于：Ultrasound in Obstetrics and Gynecology · 年份：2025 · DOI：10.1002/uog.29234 · 被引用次数：7 · 研究领域：Pregnancy and preeclampsia studies、Gestational Diabetes Research and Management、Neonatal and fetal brain pathology

OBJECTIVE: The aims of this study were to define normative values of fetal body volume (FBV) measured using magnetic resonance imaging (MRI) from 16 to 36 gestational weeks (GW), to assess our MRI-based estimated fetal weight (EFW) using ultrasound (US)-based EFW as reference, and to compare it with EFW derived from previously published MRI- or computed tomography (CT)-based formulae. METHODS: This single-center prospective substudy of the ongoing Lumiere on the Fetus trial included healthy pregnant women with a healthy, singleton, 16-36-week fetus evaluated between December 2021 and June 2022. FBV was measured using MRI with manual segmentation of T2-weighted images. Based on our previous work, we defined MRI-FBV as being equal to MRI-derived EFW. These measurements were compared to US-EFW that was determined using Hadlock's formula < 7 days prior to MRI, by calculating the difference between them (MRI-EFW - US-EFW) and the relative error of MRI-EFW using US-EFW as the gold standard ((MRI-EFW - US-EFW)/US-EFW) × 100)). We also compared with US-EFW the performance of a further four previously published MRI- or CT-based formulae to estimate fetal weight. RESULTS: ) + (0.103 × FBV) + 113.13. The mean ± SD difference between MRI-EFW and US-EFW was -27.58 ± 127.35 g for Baker's formula, -57.54 ± 130.19 g for Kacem's formula, 142.51 ± 120.12 g for Amgalan's formula, -113.43 ± 150.21 g for Debbi's formula and 12.65 ± 166.37 g for our model. The mean relative error on comparison of ...