Racial/ethnic disparities in tuberculosis incidence linked to PM2.5 constituents and their sources in the United States, 2000 − 2019: a population-based study

作者：Panpan Zhu, Zi-Yang Gong, Jinhui Li, Xiaofeng Ma, Yuxiang Long, Jia-Dong Ning, Chun‐Quan Ou, Li L · 发表于：BMC Infectious Diseases · 年份：2025 · DOI：10.1186/s12879-025-11141-9 · 被引用次数：2 · 研究领域：Air Quality and Health Impacts、Climate Change and Health Impacts、Migration, Health and Trauma

Racial/ethnic disparities in the effects of PM 2.5 constituents and their sources on tuberculosis (TB) incidence remain unclear. We collected data on TB incidence in 49 states of the United States (US) during 2000 − 2019. Two-way fixed effects models were employed to assess the effects of 15 PM 2.5 constituents, and the non-negative matrix factorization analysis was additionally performed to explore the effects of sources of PM 2.5 constituents. The generalized weighted quantile sum method was applied to determine the relative contribution of each PM 2.5 constituent. Racial/ethnic disparities were evaluated in the form of absolute and relative disparities. Effects of most PM 2.5 constituents on TB incidence in the Hispanic people were stronger than those in others, with an interquartile range increase in constituents associated with 1.25 (95% CI: 0.48 to 2.02 for potassium) to 4.10 (95% CI: 3.27 to 4.94 for sulfate) additional TB cases per 100,000 individuals annually in the Hispanic people. The absolute disparity in PM 2.5 -attributable TB burden between the Hispanic and White people decreased from 11.07 to 6.48 cases per 100,000 individuals, while the relative disparity enlarged from 15.75 in 2000 to 16.17 in 2019. Sulfate was the most influential constituent to TB incidence for the White (32.0%), Hispanic people (26.1%), and people of other races/ethnicities (17.9%). PM 2.5 from oil combustion/motor vehicle traffic increased TB incidence in the Hispanic people and people o...