Research progress in material preparation and application of magnetism-enhanced in-tube solid-phase microextraction

作者：Yana Luo, Jia Chen, Yuyu Hu, Shi-Jie Gao, Yanli Wang, Yanming Liu, Juanjuan Feng, Min Sun · 发表于：Chinese Journal of Chromatography · 年份：2025 · 被引用次数：2 · 研究领域：Analytical chemistry methods development、Radioactive element chemistry and processing、Electrochemical Analysis and Applications

Selecting a suitable sample preparation method is a significant step prior to chromatographic separation and detection. Directly analyzing samples instrumentally is difficult owing to the complexity of the sample matrix and the trace concentration of analytes. Most sample preparation methods have disadvantages， including complicated operating procedures， the use of large amounts of organic solvent， and ease of analyte loss during multistep processes； consequently， they do not meet the high analytical sample detection requirements of modern industry. The development of simple， environmentally friendly， efficient， and rapid preparation methods is a continuing frontier research area in the analytical chemistry field. Among the many available sample preparation techniques， in-tube solid-phase microextraction （IT-SPME） is receiving extensive attention. IT-SPME enriches the target analytes by extracting them to the inner surface of the capillary tube， and has been applied to extract various analytes in the environmental and food fields. IT-SPME is advantageous because it consumes low amounts of organic solvent and capillaries are mechanical stable； consequently， IT-SPME is a promising sample preparation technique. Magnetic field has been introduced to the IT-SPME system to further improve extraction efficiency and selectivity， leading to the development of magnetism-enhanced in-tube solid-phase microextraction （ME-IT-SPME） as a new technology. ME-IT-SPME uses magnetic field to sepa...