Recycled Sericin Biopolymer in Biotechnology and Bioelectronics

作者：Davide Vurro, Aris Liboà, Ilenia D’Onofrio, Giuseppe De Giorgio, Zirong Zhou, Vardan Galstyan, Yajie Qin, Xiongchuan Huang, Pasquale D’Angelo, Giuseppe Tarabella · 发表于：Bioengineering · 年份：2025 · DOI：10.3390/bioengineering12050547 · 被引用次数：6 · 研究领域：Silk-based biomaterials and applications、Electrospun Nanofibers in Biomedical Applications、Polymer Surface Interaction Studies

In a world characterized by rapid industrialization and a growing population, plastic or polymeric waste handling has undergone significant transformations. Recycling has become a major strategy where silk sericin has great potential among recyclable polymers. This naturally occurring biopolymer is a sustainable and versatile material with a wide range of potential uses in biotechnology and sensing. Furthermore, preparing and studying new environmentally friendly functional polymers with attractive physicochemical properties can open new opportunities for developing next-generation materials and composites. Herein, we provide an overview of the advances in the research studies of silk sericin as a functional and eco-friendly material, considering its biocompatibility and unique physicochemical properties. The structure of silk sericin and the extraction procedures, considering the influence of preparation methods on its properties, are described. Sericin's intrinsic properties, including its ability to crosslink with other polymers, its antioxidative capacity, and its biocompatibility, render it a versatile material for multifunctional applications across diverse fields. In biotechnology, the ability to blend sericin with other polymers enables the preparation of materials with varied morphologies, such as films and scaffolds, exhibiting enhanced mechanical strength and anti-inflammatory effects. This combination proves particularly advantageous in tissue engineering and woun...