Safety and pharmacokinetics of N6LS, a broadly neutralising monoclonal antibody for HIV: a phase 1, open-label, dose-escalation study in healthy adults

作者：Richard L Wu, Katherine V. Houser, Martin R. Gaudinski, Alicia T. Widge, Seemal F. Awan, Cristina Carter, LaSonji A. Holman, Jamie Saunders, Cynthia S. Hendel, Aba Mensima Eshun, William R Whalen, Xiaolin Wang, Anita Arthur, Jennifer E. Cunningham, Allison Beck, Joseph P. Casazza, Galina V. Yamshchikov, Ro Shauna Rothwell, Larisa Strom, Tejaswi Dittakavi, Myra Happe, Somia P. Hickman, Michelle Conan-Cibotti, Kevin Carlton, Lily Zhang, Yunda Huang, Edmund V. Capparelli, Mike Castro, Bob C. Lin, Sarah O’Connell, Britta Flach, Robert T. Bailer, Sandeep Narpala, Leonid Serebryannyy, Adrian B. McDermott, Frank Arnold, Jason G. Gall, Sandra Vazquez, Nina M. Berkowitz, Ingelise J. Gordon, Grace L Chen, Peter D. Kwong, Jinghe Huang, Theodore C. Pierson, Mark Connors, John R. Mascola, Tongqing Zhou, Nicole A. Doria‐Rose, Richard A. Koup, Lesia Dropulic, Julie E. Ledgerwood, Barney S. Graham, Emily E. Coates, Krisha McKee, Mark Louder, Amarendra Pegu, Niharika Shah, Floreliz Mendoza, Pamela Costner, Laura Novik, Kathy Zephir, Brenda Larkin, Sarah Plummer, Abidemi Ola, Preeti Apte, Cora Trelles Cartagena, Renunda Dyer, Pernell Williams, Shinyi Telscher, Colin Tran, Olga Vasilenko, Karen Parker, Priya Kamath, Jennifer Phipps, Olympia Hotobah-During, Jackie Stephens, Justine Jones, Jumoke Gbadebo, Catina Evans, Sandra Sitar, Christian Buettner, Sana Waheed, Maria Burgos Florez, Eugeania Burch, Lam Le, Olga Trofymenko, Patricia Morgan, Mark O'Callahan, Ellie Seo, Lauren Brant, Iris Pittman, Katherine Brooks, Martha Nason, Ana Villa-Ortega, Thuy Nguyen, Alison Taylor, Lucio Gama, Florence Kaltovich, Jason Sands, Christopher Case, Judy Stein · 发表于：The Lancet HIV · 年份：2025 · DOI：10.1016/s2352-3018(25)00041-4 · 被引用次数：10 · 研究领域：HIV Research and Treatment、HIV/AIDS drug development and treatment、Biological Research and Disease Studies