Wearable, Breathable, and Wireless Gas Sensor Enables Highly Selective Exhaled Ammonia Detection and Real-Time Noninvasive Illness Diagnosis

作者：Haipeng Dong, Xiaowei Li, Xiaowei Li, Yu Liu, Wanying Cheng, Chaohan Han, Yunpeng Yin, Xinghua Li, Xinghua Li, Changlu Shao, Yichun Liu · 发表于：ACS Sensors · 年份：2025 · DOI：10.1021/acssensors.4c03468 · 被引用次数：16 · 研究领域：Gas Sensing Nanomaterials and Sensors、Advanced Chemical Sensor Technologies、Analytical Chemistry and Sensors

Wearable gas sensors capable of real-time analysis of exhaled breath have been identified as ideal devices for noninvasive illness diagnosis. However, due to their inherent rigidity and brittleness, as well as high cross-sensitivity, conventional semiconductor gas sensors face significant challenges in achieving high flexibility, robustness, and selective exhaled breath analysis. Herein, we propose a wearable gas sensor by anchoring a SnS 2 nanosheets/polyaniline (PANI) sensing layer in situ onto a permeable and flexible yttria-stabilized zirconia (YSZ) nanofiber substrate for the analysis of exhaled NH 3 . The cross-linked meshes of the YSZ network and the abundant voids between SnS 2 nanosheets effectively release the stress concentration in YSZ/SnS 2 /PANI films, enabling the sensor to withstand severe folding/bending deformation. The organic PANI sheath endows the YSZ/SnS 2 /PANI-based gas sensor with enhanced toughness (0.66 kJ·m –3 ), stable electrical connection, and excellent robustness. The unique protonation/deprotonation sensing mechanism, coupled with the heterojunction effect of the sensing layer, ensures outstanding selectivity (sensor immunity coefficient ≈ 69%) and a high response to NH 3 . To support wearable applications, the sensing signals from the wearable sensor are transmitted wirelessly via Bluetooth and displayed on a smartphone. This work greatly advances the application of a wearable semiconductor sensor in personal disease diagnosis.