Machine-Learning Assisted Screening with FIND FH for Familial Hypercholesterolemia among Youth

作者：Kerrilynn C. Hennessey, Mary P. McGowan, Hanyuan Shi, Terry Sturke, Roshni S. Kalkur, Adam J. Prince, Shoshana H. Bardach, Nichole M. Rogovoy, Marc A. Hofley · 发表于：The Journal of Pediatrics · 年份：2025 · DOI：10.1016/j.jpeds.2025.114640 · 被引用次数：3 · 研究领域：Lipoproteins and Cardiovascular Health、Diabetes, Cardiovascular Risks, and Lipoproteins、Lipid metabolism and disorders

Although the American Academy of Pediatrics recommends universal lipid screening among children to find cases of familial hypercholesterolemia, such screening is rarely performed. We report the first clinical use of a novel machine learning model (FIND FH) to identify youth at increased risk of familial hypercholesterolemia and results from the associated outreach.